Low‑Carb Pizza Casserole (Gluten‑Free and Diabetes Friendly)

Servings: 6 Total Time: 40 mins
All the flavors of pizza in a simple, gluten‑free, diabetes‑friendly casserole.

Low‑Carb Pizza Casserole (Gluten‑Free and Diabetes Friendly)

Prep Time 15 mins Cook Time 25 mins Total Time 40 mins
Cooking Temp: 375  C Servings: 6 Calories: 290

Description

This Low Carb Pizza Casserole has all the flavors of your favorite pizza, but in a simple, gluten‑free, diabetes‑friendly bake that comes together fast. Made with lean ground turkey or beef, marinara, over 2 cups of veggies, and plenty of melty mozzarella, it’s a cozy weeknight dinner that supports balanced blood sugars without sacrificing flavor. It’s high‑protein, family‑friendly, and perfect for anyone who wants a satisfying meal that fits into a low‑carb lifestyle. You can serve it by itself, over spaghetti squash, regular pasta or with a slice of garlic bread of choice.

Ingredients You'll Need

Instructions

  1. Preheat oven to 375°F.
  2. In a large skillet, brown the ground turkey or beef over medium heat. Drain excess fat if needed.
  3. Add bell pepper and mushrooms and cook 3–4 minutes until slightly softened.
  4. Stir in Italian seasoning, garlic powder, salt, and pepper.
  5. Pour in the marinara and stir to combine. Simmer 2 minutes.

Assemble the casserole:

  1. Transfer mixture to an 8×8 or 9×9 baking dish.
  2. Top with mozzarella cheese, and pepperoni slices.
  3. Bake 18–22 minutes, or until cheese is melted and bubbly with lightly browned edges.
  4. Let cool 5 minutes before slicing. Serve with a simple side salad or roasted veggies.

Nutrition Facts

Servings 6


Amount Per Serving
Calories 290kcal
% Daily Value *
Total Fat 19.5g30%
Saturated Fat 7g35%
Sodium 405mg17%
Total Carbohydrate 8g3%
Dietary Fiber 2g8%
Sugars 1.8g
Protein 20g40%

* Percent Daily Values are based on a 2,000 calorie diet. Your daily value may be higher or lower depending on your calorie needs.

Note

Keywords: Gluten-free, Low-carb, Diabetes-friendly dinner, Family-friendly, Kid-friendly
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Is there a way to lower the fat in the dish?

Expand All:

Can I add pasta?

Yes! I usually cook a pot of pasta and serve the casserole over it for my kids. However, you're welcome to cook the pasta first, then add to the casserole when cooking. I would add around 1-1/2 cups cooked and increase the baking time by about 5 minutes. 

Can I make this ahead of time?

Absolutely. You can prep the meat mixture up to 2 days in advance, store it in the fridge, then assemble and bake when ready. Leftovers also reheat really well.

Can I freeze it?

Yes! I would bake first, then cover tightly and freeze. You can keep it in the freezer up to 3 months. Cook at 350 for 35-45 minutes (cover the first 25 minutes).

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